What’s the meaning of drug manufacturing os?

What is the meaning of the gold standard os

Safety mark.

1, os logo is the food quality and safety of the market quasi-people mark, its style and use by the State General Administration of Quality Supervision, Inspection and Quarantine unified development, the logo by the “quality and safety” in English (qualitysafety) prefix os and the “Quality and Safety “Chinese characters.

2, the main color of the logo is blue, the letter “q” and “quality and safety” four Chinese characters in blue, the letter “s” in white, when used according to the need to enlarge or reduce the proportion, but shall not be deformed. Proportionally enlarged or reduced, but shall not be deformed, discolored. Foods labeled (printed) with the “os” mark mean that the food complies with the safety standards.

[help]Can any of you summarize the abbreviations that appear in all drug clinical trials? ~

Commonly used abbreviations in clinical trials TTP: time-to-progression time of disease progression SAE: severityAdverseEvent serious adverse event AE: AdverseEvent adverse event SOP: StandardOperatingProcere Standard Operating Procedure CRF:CaseReportForm Case Report Form DLT:Dose Limiting Toxicity MTD:Maximum Tolerated Dose KPS:KarnofskyPerformanceStatus Behavioral Status Score CR:completeresponse Complete Remission PR:partialresponse Partial Remission SD:Stable Disease Stabilization PD: progressivedisease condition progression CTC: Commonly used drug toxicity criteria IEC: independentethicscommittee Independent Ethics Committee IRB: institutionalreviewboard Ethics Committee CRA: Clinical Research Associate CRO: ContractResearchOrganization DFS: DiseaseFreeSurvival OS: (OverallSurvival) Overall Survival Time IC: Informedconsent Informed Consent ADR: AdverseDrugReaction Adverse Reaction GLP: Good Practice for the Management of Nonclinical Safety Trials GCP: Good Practice for the Quality Management of Drug Clinical Trials GMP: Good Practice for the Quality Management of Drug Manufacturing GAP: Good Practice for the Quality Management of Chinese Herbal Medicines Production GSP: Good Practice for the Quality Management of Drug Businesses DGMP: Good Practice for the Quality Management of Medical Device Manufacturing ICF: Informedconsentform informed consent RCT: randomizedcontrolledtrial randomized controlled trial NRCCT: non-randomizedconcurrentcontrolledtrial non-randomized contemporaneous controlled trial EBM: evidence-basedmedicine evidence-based medicine basedmedicineevidence-basedmedicine RCD: randomizedcross-overdisgnandomizedcrossovercontrolledtrial HCT: historicalcontroltrialhistoricalcontrolledstudy RECIST:

What does os supplier mean

Os suppliers are firms and individuals who supply a variety of resources needed by a firm and its competitors, including the provision of raw materials, equipment, energy, labor, and so on.

How their situation will have a huge impact on the enterprise’s marketing activities, such as changes in raw material prices, shortages, etc. will affect the price of the enterprise’s products and delivery time, and will thus weaken the long-term cooperation between the enterprise and its customers with the interests of the marketer, therefore, the marketer must have a more comprehensive understanding of the situation of the supplier and a thorough analysis. Suppliers are both business negotiations in the opponent is a partner.

“Retailer supplier fair trade management approach” provides that: suppliers are directly to the retailer to provide goods and services to the enterprise and its branches, individual businesses, including manufacturers, distributors and other intermediaries. It is also referred to as “vendor”, i.e., an individual or legal entity that supplies goods.

Suppliers can be farmers, production bases, manufacturers, agents, wholesalers (limited to the first level), importers, etc., should be avoided too many intermediate suppliers. For example: secondary wholesalers, distributors, skin bag companies (dumpers), or companies run by friends and relatives.

Supplier Replacement Costs

1. Purchasing Process Costs

2. Costs of Introduction/Extermination

Specific costs may be related to: inventory, tooling, and equipment stocking; completing ordered batches; disposing of leftover and subsequently rejected products; detailed handover of on-going projects; replacing systems and interfaces; and meeting and establishing new relationships and very professionally ending old relationships.

3. Transaction costs

New costs are incurred as the duration of the relationship increases leading to changes in the transaction phase. Secondly, transaction costs are affected by the frequency of transactions, transaction uncertainty and asset specialization.

Refer to Baidu Encyclopedia-Vendor; Baidu Encyclopedia-Supplier

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What is OS/PPAP Sample

0S is a stage in APQP

It is called differently by each automobile manufacturer, just like the usual prototype stage/pilot production stage/production stage.

OS prototype means one stage of prototype. You can ask the customer what the specific requirements are.

What do MDS and QCOS mean in PPAP?

Multidimensional scaling (MDS)

MDS is a set of analytic methods for representing the perceptions and preferences of a research subject by means of an intuitive spatialmap.

It uses points in multidimensional space to represent perceptual or psychometric relationships between different stimuli, a geometric representation known as a spatial map. The axes of the spatial map are generally considered to represent the psychological basis or underlying dimensions of the perceptions and preferences formed by the respondents to the stimuli.

In marketing, the MDS can be used to identify:

1. the number and nature of dimensions perceived by consumers for different brands

2. the positioning of existing brands on these dimensions

3. the positioning of consumers’ ideal brands on these dimensions


Myelodysplastics Syndrome

The MDS is a tool that can be used to determine the extent to which consumers perceive different brands to be different. Myelodysplasticsyndrome (MDS) is a group of heterogeneous clonal disorders originating from hematopoietic myeloid directed stem cells or pluripotent stem cells, which is mainly characterized by ineffective hematopoiesis and high-risk of evolving into acute myeloid leukemia, and is clinically manifested by varying degrees of qualitative and quantitative abnormalities in hematopoietic cells. The specific clinical manifestations are anemia, which may be accompanied by infection or bleeding and may be asymptomatic in some patients. Some patients may have mild enlargement of the liver, spleen and lymph nodes, and a few may have sternal pressure, rib or limb arthralgia. The blood picture may show thrombocytopenia of whole blood cells, or any one or two blood cell lines. The name of the disease was established in 1982 by the FAB Collaborative Group recommendation, and MDS was divided into five types: refractory anemia; refractory anemia with cyclic iron granulocytosis; refractory anemia with primitive cellularity, refractory anemia with primitive cellularity in the transition; and chronic granulocytic-mononuclear cell leukemia.

The incidence of MDS is about 10/100,000 to 12/100,000 population, mostly affecting the middle-aged and the elderly, with 50% to 70% of cases over 50 years of age, and the ratio of men to women is 2:1. 30% to 60% of MDS is transformed into leukemia. In addition to leukemia, most deaths are due to infection, bleeding, especially intracranial hemorrhage.


The etiology of MDS is unclear, and it is hypothesized to be due to biological, chemical, or physical factors that cause genetic mutations and chromosomal abnormalities that result in the clonal proliferation of a malignant cell. It is well established that mutagens such as viruses, certain drugs (e.g., chemotherapeutic agents), radiation (radiotherapy), industrial reactants (e.g., benzene, polyethylene), and environmental pollutants can be carcinogenic, and that mutagens can cause chromosomal rearrangements or gene rearrangements, or they may only cause alterations in gene expression that lead to MDS.

MDS is a malignant disease that develops when a single, abnormal hematopoietic stem cell gives rise to a “clone”, as is the case in acute leukemia. MDS, like acute leukemia, is a “clonal disease” that develops from a malignant clone derived from an abnormal hematopoietic stem cell. It mainly involves myeloid cells, resulting in ineffective hematopoiesis of myeloid granulocytic, erythroid, and megakaryocytic lineages, with a marked increase in the number of apoptotic cells. Answer Supplement PPAP=PRODUCTIONPARTAPPROVALPROCESS

ProctionPartApprovalProcess Production Part Approval Process

That is, the Production Part Approval Process, which requires that production be done on schedule and that prototypes be made to verify production capability.

PPAP production parts submitted to the guarantee: the main production parts size inspection report, appearance inspection report, functional inspection report, material inspection report; plus some parts control methods and supplier control methods; mainly manufacturing companies require suppliers to submit the product to do the PPAP file and the first, only when the ppap file can be submitted after all qualified; when the engineering changes must be submitted to the report. submit a report.

PPAP is a control program for production parts and a management method for quality.